| CODE | PHR1602 | ||||||||||||
| TITLE | Compounding and Mathematical Principles | ||||||||||||
| UM LEVEL | 01 - Year 1 in Modular Undergraduate Course | ||||||||||||
| MQF LEVEL | 5 | ||||||||||||
| ECTS CREDITS | 6 | ||||||||||||
| DEPARTMENT | Pharmacy | ||||||||||||
| DESCRIPTION | Basic Principles of Mathematics • Fractions • Decimals • Ratios • Percentages • The Metric System • Conversion of weight units • Conversion of volume units Principles of Compounding • Accuracy of measurements: Number of significant figures; Accuracy in calculations; Accuracy when weighing or measuring during extemporaneous preparation handling and in the laboratory • Use of mechanical and electronic balances for compounding • Introduction to British Pharmacopoeia • Guidance on compounding: BP and FDA compliance • Techniques used to prepare and dispense extemporaneous preparations • Uniformity of product • Requirements and parts of a prescription label Mathematical Principles of Compounding • Calculations involving concentration: Amount Strength; Ratio Strength; Parts per million; Percentage concentration • Calculations involving dilutions • Density, displacement volumes, displacement values • Calculations involving molecular weight • Calculation of Dosages: Topical preparations; Oral preparations; Parenteral solutions; Based on body weight; Based on surface area • Isotonicity when preparing parenteral solutions Compounding practical demonstrations Study-unit Aims: • To establish and to consolidate the mathematical principles required in pharmaceutical science; • To introduce the student to the use of drugs to treat disease as well as to the dangers emanating from administering incorrect doses of the drugs The importance of giving the appropriate drug of the right quality at the right dose to the right patient at the right time will be emphasised; • To expose the student to the importance of following the British Pharmacopoeia or prescription correctly during compounding; • To expose the student to the the calculations needed to compound pharmaceutical products from raw materials and commercial products. Learning Outcomes: 1. Knowledge & Understanding: By the end of the study-unit the student will be able to: • Interpret units and dilution factor; • Understand instructions for extemporaneous preparations. 2. Skills: By the end of the study-unit the student will be able to: • Undertake mathematical skills required in pharmaceutical preparation; • Calculate doses; • Prepare dilutions; • Apply the mathematical skills to prepare extemporaneous preparations and bulk ingredients in manufacture of pharmaceuticals. Main Text/s and any supplementary readings: • Ansel HC. Pharmaceutical Calculations. USA: Lippincott, Williams and Wilkins. 2009. 978-1582558370 • British Pharmacopoeia Commission Secretariat of the Medicines and Healthcare products Regulatory Agency. British Pharmacopoeia. London: The Stationery Office; 2011. ISBN 9780113228492 • Langley C, Belcher D. Pharmaceutical compounding and dispensing. London: Pharmaceutical Press. 2008 ISBN 978 085369 7008 • Mohr ME. Standards of Practice for the Pharmacy Technician. 1st ed. USA: Lippincott Williams & Wilkins; 2009 • Moini J. Comprehensive exam review for the pharmacy technician. New York: Thomson Delmar Learning; 2005 • Rees JA, Smith I. Pharmaceutical Calculations Workbook. London: Pharmaceutical Press; 2006. p. 271-302 • Rees JA, Smith I, Smith B. Introduction to Pharmaceutical Calculations. London: Pharmaceutical Press; 2006. |
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| STUDY-UNIT TYPE | Lecture | ||||||||||||
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| LECTURER/S | Alison Anastasi Nicolette Sammut Bartolo Marie Claire Zammit |
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The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years. |
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