Showing results 65 to 115 of 115
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| Issue Date | Title | Author(s) |
| 2019 | Kinase activity is impaired in neutrophils of sepsis patients | Hoogendijk, Arie J.; Vught, Lonneke A. van; Wiewel, Maryse A.; Fuhler, Gwenny M.; Belkasim-Bohoudi, Hakima; Horn, Janneke; Schultz, Marcus J.; Scicluna, Brendon P.; Peppelenbosch, Maikel P.; Veer, Cornelis Van't; Vos, Alex F. de; Poll, Tom van der |
| 2020 | The leukocyte non-coding RNA landscape in critically ill patients with sepsis | Scicluna, Brendon P.; Uhel, Fabrice; Vught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Baessman, Ingelore; Franitza, Marek; Nürnberg, Peter; Horn, Janneke; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium |
| 2019 | Leukocyte transcriptional signatures dependent on LPS dosage in human endotoxemia | Khan, Hina N.; Perlee, Desirée; Schoenmaker, Lieke; Meer, Anne-Jan van der; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Zwinderman, Aeilko H.; Poll, Tom van der; Scicluna, Brendon P. |
| 2011 | Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice | Fabritz, Larissa; Hoogendijk, Mark G.; Scicluna, Brendon P.; Amersfoorth, Shirley C.M. van; Fortmueller, Lisa; Wolf, Susanne; Laakmann, Sandra; Kreienkamp, Nina; Piccini, Ilaria; Breithardt, Günter; Ruiz Noppinger, Patricia; Witt, Henning; Ebnet, Klaus; Wichter, Thomas; Levkau, Bodo; Franke, Werner W.; Pieperhoff, Sebastian; Bakker, Jacques M. T. de; Coronel, Ruben; Kirchhof, Paulus |
| 2022 | The long non-coding antisense RNA JHDM1D-AS1 regulates inflammatory responses in human monocytes | Malmström, Erik; Khan, Hina N.; Veer, Cornelis van’t; Stunnenberg, Melissa; Meijer, Mariska T.; Matsumoto, Hisatake; Otto, Natasja A.; Geijtenbeek, Teunis B. H.; Vos, Alex F. de; Poll, Tom van der; Scicluna, Brendon P. |
| 2019 | Matrix metalloproteinase-8 : a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission? | Uhel, Fabrice; Scicluna, Brendon P.; Vught, Lonneke A. van; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der |
| 2015 | Modular transcriptional networks of the host pulmonary response during early and late pneumococcal pneumonia | Scicluna, Brendon P.; Lieshout, Miriam H. van; Blok, Dana C.; Florquin, Sandrine; Poll, Tom van der |
| 2018 | Molecular biomarker to assist in diagnosing abdominal sepsis upon ICU admission | Scicluna, Brendon P.; Wiewel, Maryse A.; Vught, Lonneke A. van; Hoogendijk, Arie J.; Klarenbeek, Augustijn M.; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Horn, Janneke; Bonten, Marc M.J.; Schultz, Marcus J.; Cremer, Olaf L.; Poll, Tom van der |
| 2015 | A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission | Scicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Vught, Lonneke A. van; Wiewel, Maryse A.; Ong, David S.Y.; Zwinderman, Aeilko H.; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Hoogendijk, Arie J.; Horn, Janneke; Cremer, Olaf L.; Schultz, Marcus J.; Bonten, Marc M.J.; Poll, Tom van der |
| 2015 | A molecular host response assay to discriminate between sepsis and infection-negative systemic inflammation in critically ill patients : discovery and validation in independent cohorts | McHugh, Leo C.; Seldon, Therese A.; Brandon, Roslyn A.; Kirk, James T.; Rapisarda, Antony; Sutherland, Allison J.; Presneill, Jeffrey J.; Venter, Deon J.; Lipman, Jeffrey; Thomas, Mervyn R.; Klein Klouwenberg, Peter M.C.; Vught, Lonneke A. van; Scicluna, Brendon P.; Bonten, Marc M.J.; Cremer, Olaf L.; Schultz, Marcus J.; Poll, Tom van der; Yager, Thomas D.; Brandon, Richard B. |
| 2020 | Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study | Uhel, Fabrice; Peters-Sengers, Hessel; Falahi, Fahimeh; Scicluna, Brendon P.; Vught, Lonneke A. van; Bonten, Marc M.J.; Cremer, Olaf L.; Schultz, Marcus J.; Poll, Tom van der; MARS Consortium |
| 2022 | Myeloid cell tet methylcytosine dioxygenase 2 does not affect the host response during gram-negative bacterial pneumonia and sepsis | Qin, Wanhai; Brands, Xanthe; Veer, Cornelis Van't; Vos, Alex F. de; Scicluna, Brendon P.; Poll, Tom van der |
| 2022 | Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation | Qin, Wanhai; Arnold Spek, C.; Scicluna, Brendon P.; Poll, Tom van der; Duitman, JanWillem |
| 2009 | Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy | Pilichou, Kalliopi; Remme, Carol Ann; Basso, Cristina; Campian, Maria E.; Rizzo, Stefania; Barnett, Phil; Scicluna, Brendon P.; Bauce, Barbara; Hoff, Maurice J. B. van den; Bakker, Jacques M. T. de; Tan, Hanno L.; Valente, Marialuisa; Nava, Andrea; Wilde, Arthur A. M.; Moorman, Antoon F. M.; Thiene, Gaetano; Bezzina, Connie R. |
| 2014 | NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumonia | Lieshout, Miriam H. van; Scicluna, Brendon P.; Florquin, Sandrine; Poll, Tom van der |
| 2022 | Patients with hypothermic sepsis have a unique gene expression profile compared to patients with fever and sepsis | Harmon, Matthew B. A.; Scicluna, Brendon P.; Wiewel, Maryse A.; Schultz, Marcus J.; Horn, Janneke; Cremer, Olaf L.; Poll, Tom van der; Joost Wiersinga, W.; Juffermans, Nicole P.; MARS Consortium |
| 2019 | A pilot study of a novel molecular host response assay to diagnose infection in patients after high-risk gastro-intestinal surgery | Verboom, Diana M.; Koster-Brouwer, Maria E.; Ruurda, Jelle P.; Hillegersberg, Richard van; Berge Henegouwen, Mark I. van; Gisbertz, Suzanne S.; Scicluna, Brendon P.; Bonten, Marc M.J.; Cremer, Olaf L.; MARS Consortium |
| 2021 | Plasma ferritin as marker of macrophage activation-like syndrome in critically ill patients with community-acquired pneumonia | Brands, Xanthe; Vries, Floris M. C. de; Uhel, Fabrice; Haak, Bastiaan W.; Peters-Sengers, Hessel; Schuurman, Alex R.; Engelen, Tjitske S.R. van; Lutter, René; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Scicluna, Brendon P.; Poll, Tom van der; MARS Consortium |
| 2015 | Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients | Hoogendijk, Arie J.; Wiewel, Maryse A.; Vught, Lonneke A. van; Scicluna, Brendon P.; Belkasim-Bohoudi, Hakima; Horn, Janneke; Zwinderman, Aeilko H.; Klein Klouwenberg, Peter M.C.; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; MARS Consortium |
| 2020 | Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice | Ding, Chao; Scicluna, Brendon P.; Stroo, Ingrid; Yang, Jack; Roelofs, Joris J. T. H.; Boer, Onno J. de; Vos, Alex F. de; Nürnberg, Peter; Revenko, Alexey S.; Crosby, Jeff; Veer, Cornelis Van't; Poll, Tom van der |
| 2008 | The primary arrhythmia syndromes : same mutation, different manifestations. Are we starting to understand why? | Scicluna, Brendon P.; Wilde, Arthur A. M.; Bezzina, Connie R. |
| 2017 | Prior use of calcium channel blockers is associated with decreased mortality in critically ill patients with sepsis : a prospective observational study | Wiewel, Maryse A.; Vught, Lonneke A. van; Scicluna, Brendon P.; Hoogendijk, Arie J.; Frencken, Jos F.; Zwinderman, Aeilko H.; Horn, Janneke; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium |
| 2021 | Protease-activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinoma | Tekin, Cansu; Scicluna, Brendon P.; Lodestijn, Sophie C.; Shi, Kun; Bijlsma, Maarten F.; Arnold Spek, C. |
| 2003 | Proteomic detection of globin gene expression nuclear factors : implementation of an HPLC-CE two-dimensional separation system. | Scicluna, Brendon P. |
| 2011 | Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse | Scicluna, Brendon P.; Tanck, Michael W.T.; Remme, Carol Ann; Beekman, Leander; Coronel, Ruben; Wilde, Arthur A. M.; Bezzina, Connie R. |
| 2021 | Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia : an exploratory study | Kullberg, Robert F. J.; Hugenholtz, Floor; Brands, Xanthe; Kinsella, Cormac M.; Peters-Sengers, Hessel; Butler, Joe M.; Deijs, Martin; Klein, Michelle; Faber, Daniël R.; Scicluna, Brendon P.; Poll, Tom van der; Hoek, Lia Van der; Joost Wiersinga, W.; Haak, Bastiaan W. |
| 2022 | Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization | Kullberg, Robert F.J.; Brands, Xanthe; Klarenbeek, Augustijn M.; Butler, Joe M.; Otto, Natasja A.; Faber, Daniël R.; Scicluna, Brendon P.; Poll, Tom van der; Joost Wiersinga, W.; Haak, Bastiaan W. |
| 2015 | Reduced responsiveness of blood leukocytes to lipopolysaccharide does not predict nosocomial infections in critically ill patients | Vught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Scicluna, Brendon P.; Belkasim-Bohoudi, Hakima; Horn, Janneke; Schultz, Marcus J.; Poll, Tom van der |
| 2015 | Reply : comprehensive validation of the FAIM3:PLAC8 ratio in time-matched public gene expression data | Scicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Poll, Tom van der |
| 2016 | Reply : FAIM3:PLAC8 ratio compared with existing biomarkers for diagnosis of severe community-acquired pneumonia: comparing apples to oranges? | Scicluna, Brendon P.; Vught, Lonneke A. van; Poll, Tom van der; Klein Klouwenberg, Peter M.C.; Cremer, Olaf L. |
| 2022 | Resolving patient heterogeneity in critical illness requires multi-scale approaches | Scicluna, Brendon P. |
| 2016 | Risk factors, host response and outcome of hypothermic sepsis | Wiewel, Maryse A.; Harmon, Matthew B.; Vught, Lonneke A. van; Scicluna, Brendon P.; Hoogendijk, Arie J.; Horn, Janneke; Zwinderman, Aeilko H.; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Juffermans, Nicole P.; Joost Wiersinga, W. |
| 2021 | The role of host cell DNA methylation in the immune response to bacterial infection | Qin, Wanhai; Scicluna, Brendon P.; Poll, Tom van der |
| 2021 | Role of myeloid Tet methylcytosine dioxygenase 2 in pulmonary and peritoneal inflammation induced by lipopolysaccharide and peritonitis induced by Escherichia coli | Qin, Wanhai; Brands, Xanthe; Matsumoto, Hisatake; Butler, Joe M.; Veer, Cornelis Van't; Vos, Alex F. de; Roelofs, Joris J. T. H.; Scicluna, Brendon P.; Poll, Tom van der |
| 2019 | Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice | Perlee, Desirée; Vos, Alex F. de; Scicluna, Brendon P.; Maag, Anja; Mancheño, Pablo; Rosa, Olga de la; Dalemans, Wilfried; Florquin, Sandrine; Veer, Cornelis Van't; Lombardo, Eleuterio; Poll, Tom van der |
| 2013 | Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome | Scicluna, Brendon P.; Veer, Cornelis Van't; Nieuwdorp, Max; Felsmann, Karen; Wlotzka, Britta; Stroes, Erik S.G.; Poll, Tom van der |
| 2019 | The search for efficacious new therapies in sepsis needs to embrace heterogeneity | Scicluna, Brendon P.; Kenneth Baillie, J. |
| 2015 | The selective sirtuin 1 activator SRT2104 reduces endotoxin-induced cytokine release and coagulation activation in humans | Meer, Anne-Jan van der; Scicluna, Brendon P.; Moerland, Perry D.; Lin, Jiang; Jacobson, Eric W.; Vlasuk, George P.; Poll, Tom van der |
| 2017 | Sepsis patients display a reduced capacity to activate nuclear factor-κB in multiple cell types | Hoogendijk, Arie J.; Garcia-Laorden, M. Isabel; Vught, Lonneke A. van; Wiewel, Maryse A.; Belkasim-Bohoudi, Hakima; Willem Duitman, Jan; Horn, Janneke; Schultz, Marcus J.; Scicluna, Brendon P.; Veer, Cornelis Van't; Vos, Alex F. de; Poll, Tom van der |
| 2021 | Sepsis subclasses : a framework for development and interpretation | DeMerle, Kimberley M.; Angus, Derek C.; Kenneth Baillie, J.; Brant, Emily; Calfee, Carolyn S.; Carcillo, Joseph; Chang, Chung-Chou H.; Dickson, Robert; Evans, Idris; Gordon, Anthony C.; Kennedy, Jason; Knight, Julian C.; Lindsell, Christopher J.; Liu, Vincent; Marshall, John C.; Randolph, Adrienne G.; Scicluna, Brendon P.; Shankar-Hari, Manu; Shapiro, Nathan I.; Sweeney, Timothy E.; Talisa, Victor B.; Tang, Benjamin; Taylor Thompson, B.; Tsalik, Ephraim L.; Poll, Tom van der; Vught, Lonneke A. van; Wong, Hector R.; Yende, Sachin; Zhao, Huiying; Seymour, Christopher W. |
| 2022 | Source-specific host response and outcomes in critically ill patients with sepsis : a prospective cohort study | Peters-Sengers, Hessel; Butler, Joe M.; Uhel, Fabrice; Schultz, Marcus J.; Bonten, Marc M.J.; Cremer, Olaf L.; Scicluna, Brendon P.; Vught, Lonneke A. van; Poll, Tom van der; MARS Consortium |
| 2021 | Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases | Ploeg, Esmee K. van der; Golebski, Korneliusz; Nimwegen, Menno van; Fergusson, Joannah R.; Heesters, Balthasar A.; Martinez-Gonzalez, Itziar; Kradolfer, Chantal M.A.; Tol, Sophie van; Scicluna, Brendon P.; Bruijn, Marjolein J.W. de; Boer, Geertje M. de; Tramper-Stranders, Gerdien A.; Braunstahl, Gert-Jan; IJcken, Wilfred F.J. van; Paul Nagtegaal, A.; Drunen, Cornelis M. van; Fokkens, Wytske J.; Huylebroeck, Danny; Spits, Hergen; Hendriks, Rudi W.; Stadhouders, Ralph; Bal, Suzanne M. |
| 2021 | Tenascin C has a modest protective effect on acute lung pathology during methicillin-resistant staphylococcus aureus-induced pneumonia in mice | Meijer, Mariska T.; Vos, Alex F. de; Peters-Sengers, Hessel; Scicluna, Brendon P.; Roelofs, Joris J. T. H.; Fayçal, Chérine Abou; Uhel, Fabrice; Orend, Gertraud; Poll, Tom van der |
| 2021 | Tenascin-C deficiency is associated with reduced bacterial outgrowth during Klebsiella pneumoniae-evoked pneumosepsis in mice | Meijer, Mariska T.; Vos, Alex F. de; Scicluna, Brendon P.; Roelofs, Joris J. T. H.; Abou Fayçal, Chérine; Orend, Gertraud; Uhel, Fabrice; Poll, Tom van der |
| 2016 | Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients | Claushuis, Theodora A. M.; Vught, Lonneke A. van; Scicluna, Brendon P.; Wiewel, Maryse A.; Klein Klouwenberg, Peter M.C.; Hoogendijk, Arie J.; Ong, David S.Y.; Cremer, Olaf L.; Horn, Janneke; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Zwinderman, Aeilko H.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium |
| 2021 | Transcriptional changes in alveolar macrophages from adults with asthma after allergen challenge | Yang, Jack; Scicluna, Brendon P.; Engelen, Tjitske S.R. van; Bonta, Peter I.; Majoor, Christof J.; Veer, Cornelis Van't; Vos, Alex F. de; Bel, Elisabeth H.; Poll, Tom van der |
| 2010 | Tubulin polymerization modifies cardiac sodium channel expression and gating | Casini, Simona; Tan, Hanno L.; Demirayak, Ilker; Remme, Carol Ann; Amin, Ahmad S.; Scicluna, Brendon P.; Chatyan, Houssine; Ruijter, Jan M.; Bezzina, Connie R.; Ginneken, Antoni C. G. van; Veldkamp, Marieke W. |
| 2017 | Turning a new page in sepsis molecular diagnostics necessitates context-specific biomarkers | Scicluna, Brendon P.; Poll, Tom van der |
| 2019 | Understanding heterogeneity in biologic phenotypes of acute respiratory distress syndrome by leukocyte expression profiles | Bos, Lieuwe D. J.; Scicluna, Brendon P.; Ong, David S.Y.; Cremer, Olaf L.; Poll, Tom van der; Schultz, Marcus J. |
| 2018 | Validation of a host response assay, septicyte LAB, for discriminating sepsis from systemic inflammatory response syndrome in the ICU | Miller 3rd, Russell R.; Lopansri, Bert K.; Burke, John P.; Levy, Mitchell; Opal, Steven; Rothman, Richard E.; D'Alessio, Franco R.; Sidhaye, Venkataramana K.; Aggarwal, Neil R.; Balk, Robert; Greenberg, Jared A.; Yoder, Mark; Patel, Gourang; Gilbert, Emily; Afshar, Majid; Parada, Jorge P.; Martin, Greg S.; Esper, Annette M.; Kempker, Jordan A.; Narasimhan, Mangala; Tsegaye, Adey; Hahn, Stella; Mayo, Paul; Poll, Tom van der; Schultz, Marcus J.; Scicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Rapisarda, Antony; Seldon, Therese A.; McHugh, Leo C.; Yager, Thomas D.; Cermelli, Silvia; Sampson, Dayle; Rothwell, Victoria; Newman, Richard; Bhide, Shruti; Fox, Brian A.; Kirk, James T.; Navalkar, Krupa; Davis, Roy F.; Brandon, Roslyn A.; Brandon, Richard B. |
| 2018 | Validation of a novel molecular host response assay to diagnose infection in hospitalized patients admitted to the ICU with acute respiratory failure | Koster-Brouwer, Maria E.; Verboom, Diana M.; Scicluna, Brendon P.; Groep, Kirsten van de; Frencken, Jos F.; Janssen, Davy; Schuurman, Rob; Schultz, Marcus J.; Poll, Tom van der; Bonten, Marc M.J.; Cremer, Olaf L.; MARS Consortium |
