Platelet-rich plasma injections to promote healing of soft tissue injuries

Abstract

The healing of bone and soft tissue injuries takes place in many stages. This has been one of the most exciting areas of research in orthopedic surgery and sports medicine. The initial healing stages include inflammation and cell proliferation. It is well known that platelet activation plays a key role in the process of wound and soft tissue healing. Platelet-rich plasma (PRP) is obtained from the patient’s own blood by a simple technique that increases the platelet concentration above baseline; local injection of this PRP promotes healing of injured tendons, ligaments, muscles and joints. Platelets and the liquid plasma portion of the blood contain many factors that are essential for the cell recruitment, multiplication and specialization that are required for healing.