An introduction to dark field CT (DFCT) : a game changer for the future of CT?

Abstract

Computed tomography (CT) technology has undergone rapid evolution in recent years. The introduction of photon-counting CT has already begun reshaping the fundamental principles of CT imaging. In this context of innovation, dark-field CT (DFCT) is emerging as a promising advancement, offering a new imaging contrast based on small-angle X-ray scattering rather than traditional attenuation. This article aims to explore the potential role of DFCT in medical imaging, reviewing the current state of the technology, its underlying physical principles, and the advantages demonstrated in preclinical studies, particularly in detecting microstructural changes in tissues such as the lungs and bones. Although still in the experimental phase, DFCT represents a novel and potentially transformative tool that could complement conventional CT and expand diagnostic capabilities in the future.