Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/18478
Title: The effect of benzalkonium chloride additions to AH Plus sealer. Antimicrobial, physical and chemical properties
Authors: Arias-Moliz, Maria Teresa
Ruiz-Linares, Matilde
Cassar, Glenn
Ferrer-Luque, Carmen Maria
Baca, Pilar
Ordinola-Zapata, Ronald
Camilleri, Josette
Keywords: Polymers
Polymers in medicine
Antimicrobial polymers
Issue Date: 2015
Publisher: Elsevier Ltd.
Citation: Arias-Moliz, M. T., Ruiz-Linares, M., Cassar, G., Ferrer-Luque, C. M., Baca, P., Ordinola-Zapata, R., & Camilleri, J. (2015). The effect of benzalkonium chloride additions to AH Plus sealer. Antimicrobial, physical and chemical properties. Journal of Dentistry, 43(7), 846-854.
Abstract: Objectives: The aim of this study was to determine the antimicrobial and antibiofilm activities and physicochemical properties of AH Plus sealer mixed with different concentrations of benzalk- onium chloride (BC). Methods: AHPluswas testedaloneandmixedwith1%,2%and3%ofBC.Theantimicrobialandantibiofilm activities of the sealers against Enterococcus faecalis were evaluated by the direct contact test (DCT) and by confocallaser scanningmicroscopy, respectively.Setting time,flow and solubilitywere assessed according to ANSI/ADA specifications. Microhardness and contact angle tests were also performed. The chemical changes of the sealers were evaluated by X-ray diffraction analysis, and both Fourier transform infrared spectroscopy (FT-IR) and attenuated total reflectance Fourier transform infrared (ATR FT-IR). Results: AH Plus + 3% BC was the only sealer to promote total elimination of E. faecalis and the biovolume in this group was significantly lower than in the rest of the sealers ( p > 0.05). The physical propertiesofthe sealerswereaccording totheANSI/ADAspecifications.Themicrohardnessdecreased significantly when BC was added and a significant reduction in contact angle was obtained when incorporating 2% and 3% BC ( p < 0.05). No phase changes were observed with the modified sealers. Conclusions: The addition of 2% or higher concentrations BC to AH Plus showed antimicrobial and antibiofilm activities without affecting the properties specified in ANSI/ADA standards. However, additives to the root canal sealer altered other physical and chemical properties that are not commonly found in the literature to evaluate filling materials. Clinical significance: The present study highlights that the antimicrobial properties of AH Plus can be significantly improved with the addition of BC. Testing beyond what is specified in standards may be indicated.
URI: https://www.um.edu.mt/library/oar//handle/123456789/18478
Appears in Collections:Scholarly Works - FacDenRS
Scholarly Works - FacEngMME



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