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https://www.um.edu.mt/library/oar/handle/123456789/19821| Title: | The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro : a comparative study |
| Authors: | Attard, Everaldo Scicluna-Spiteri, Anthony Grixti, Mario Cuschieri, Alfred |
| Keywords: | Cucurbitaceae Stomach -- Cancer Ovaries -- Cancer Cell lines |
| Issue Date: | 1996-07-01 |
| Publisher: | Malta Chamber of Scientists |
| Citation: | Attard, E., Scicluna-Spiteri, A., Grixti, M., & Cuschieri, A. (1996). The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro: A comparative study. Xjenza, 1(1), 29-34. |
| Abstract: | A comparative study of the cytotoxicity of cucurbitacin E, a natural product, and busulphan on human ovarian and stomach cell lines was carried out. The cells were exposed to different concentrations of these two compounds and cell viability was determined from day 0 to day 11. It was observed that cucurbitacin E had a marked effect on the ovarian cancer cell line while busulphan showed a similar effect when exposed to the stomach cancer cell line. The drug-cell combinations showed a pronounced cell kill exponential curve, leading to the conclusion that cucurbitacin E exerts its pinocytic activity on the ovarian cancer cells while busulphan exerts its alkylating effect on the stomach cancer cells. |
| URI: | https://www.um.edu.mt/library/oar//handle/123456789/19821 |
| Appears in Collections: | Scholarly Works - FacEMAPP Scholarly Works - InsESRSF |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| The_Cytotoxic_Activity_of_Cucurbitacin_E.pdf | 892.7 kB | Adobe PDF | View/Open |
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