Brenner tumour : the rare malignant variant

Abstract

Brenner tumours were first described by MacNoughton Jones in 1898 in his paper ‘Uterine fibroid with anomalous ovarian tumour.’ In 1907, Fritz Brenner published his article ‘Des oophorona folliculare’ because of the resemblance of the epithelioid nests that Brenner found in his tumour, to Graafian follicles. The semblance to Graafian follicles underpinned Fritz Brenner’s classification of Brenner tumours as a variant of granulosa cell tumour. In 1932, Meyer, revisited the topic of Brenner tumours and clarified that they are different from granulosa cell tumours. However, Brenner became aware of such a publication, 24 years later and did not publish any other articles on this subject.