Please use this identifier to cite or link to this item:
Title: Gene editing... quo vadis?
Authors: Ellul, Ian C.
Keywords: Editorials
Gene editing
Genetic engineering -- Moral and ethical aspects
Issue Date: 2018
Publisher: Medical Portals Ltd.
Citation: Ellul, I. C. (2018). Gene editing... quo vadis? The Synapse : the Medical Professionals' Network, 17(2), 3.
Abstract: As discussed in the last editorial, modern gene editing is quite precise but it is not perfect. The procedure can be hit and miss, reaching some cells but not others. Even when Crispr gets where it is needed, the edits can differ from cell to cell, for example mending two copies of a mutated gene in one cell, but only one copy in another. For some genetic diseases this may not matter, but it may if a single mutated gene causes the disorder. Another common problem happens when edits are made at the wrong place in the genome. There can be hundreds of these “offtarget” edits that can be dangerous if they disrupt healthy genes or crucial regulatory DNA.
Appears in Collections:The Synapse, Volume 17, Issue 2
The Synapse, Volume 17, Issue 2

Files in This Item:
File Description SizeFormat 
The_Synapse,_17(2)_-_Edi.pdf80.3 kBAdobe PDFView/Open

Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.