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https://www.um.edu.mt/library/oar/handle/123456789/42863
Title: | An unusual cause for fever : a case report on microscopic polyangiitis |
Authors: | Fenech, Valentina Pavia, Norma Frendo, Michaela |
Keywords: | Fever -- Case studies Glucocorticoids Fever -- Treatment Fever -- Pathogenesis |
Issue Date: | 2019-04 |
Publisher: | University of Malta. Medical School |
Citation: | Fenech, V., Pavia, N., & Frendo, M. (2019). An unusual cause for fever : a case report on microscopic polyangiitis. Malta Medical Journal, 31(1), 22-25. |
Abstract: | Microscopic polyangiitis (MPA) is a small-vessel vasculitis which results in pauci-immune necrotizing inflammation of blood vessel walls. In this report, we describe a case of MPA in a 65-year old female who presented with a 1 month history of lower back pain followed by reduced appetite, weight loss and fever. An immunology screen detected perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA) with myeloperoxidase (MPO) specificity in the serum. A renal biopsy was obtained because of mild proteinuria on urinalysis and revealed a small vessel vasculitis consistent with MPA. She is being treated with glucocorticoids and cyclophosphamide which resulted in a positive clinical response, with resolution of fever and improvement in her inflammatory markers. Currently she is stable and since starting treatment, she has not had any relapses or flare ups. |
URI: | https://www.um.edu.mt/library/oar//handle/123456789/42863 |
Appears in Collections: | MMJ, Volume 31, Issue 1 MMJ, Volume 31, Issue 1 |
Files in This Item:
File | Description | Size | Format | |
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MMJ,_31(1)_-_CR1.pdf | 1.11 MB | Adobe PDF | View/Open |
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