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Title: An unusual cause for fever : a case report on microscopic polyangiitis
Authors: Fenech, Valentina
Pavia, Norma
Frendo, Michaela
Keywords: Fever -- Case studies
Fever -- Treatment
Fever -- Pathogenesis
Issue Date: 2019-04
Publisher: University of Malta. Medical School
Citation: Fenech, V., Pavia, N., & Frendo, M. (2019). An unusual cause for fever : a case report on microscopic polyangiitis. Malta Medical Journal, 31(1), 22-25.
Abstract: Microscopic polyangiitis (MPA) is a small-vessel vasculitis which results in pauci-immune necrotizing inflammation of blood vessel walls. In this report, we describe a case of MPA in a 65-year old female who presented with a 1 month history of lower back pain followed by reduced appetite, weight loss and fever. An immunology screen detected perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA) with myeloperoxidase (MPO) specificity in the serum. A renal biopsy was obtained because of mild proteinuria on urinalysis and revealed a small vessel vasculitis consistent with MPA. She is being treated with glucocorticoids and cyclophosphamide which resulted in a positive clinical response, with resolution of fever and improvement in her inflammatory markers. Currently she is stable and since starting treatment, she has not had any relapses or flare ups.
Appears in Collections:MMJ, Volume 31, Issue 1
MMJ, Volume 31, Issue 1

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