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dc.identifier.citationMifsud Buhagiar, L., Sammut Bartolo, N., Vella Szijj, J., Ferrito, V., Serracino Inglott, A., & LaFerla, G. (2018, November). Analysis of amitriptyline and its metabolites. Poster session presented at the X Malta Medical School Conference, St Julian's, Malta.en_GB
dc.description.abstractA poster presentation regarding the analysis of amitriptyline and its metabolites. Aims: Amitriptyline, a tricyclic antidepressant, has been renowned for over half a century for its efficacy, pharmacoeconomic benefits and potential adverse effects. Most analytical procedures utilised for recommended therapeutic drug monitoring only account for amitriptyline as the parent drug and nortriptyline as the active demethylated metabolite. This project aimed to determine the hydroxylated metabolites which may prove expedient due to possible clinical effects, particularly cardiovascular toxicity.en_GB
dc.publisherUniversity of Malta. Department of Pharmacyen_GB
dc.subjectAmitriptyline -- Analysisen_GB
dc.subjectMetabolites -- Analysisen_GB
dc.subjectChromatographic analysis -- Methodologyen_GB
dc.subjectCardiovascular toxicologyen_GB
dc.titleAnalysis of amitriptyline and its metabolitesen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.contributor.creatorMifsud Buhagiar, Luana-
dc.contributor.creatorSammut Bartolo, Nicolette-
dc.contributor.creatorVella Szijj, Janis-
dc.contributor.creatorFerrito, Victor-
dc.contributor.creatorSerracino-Inglott, Anthony-
dc.contributor.creatorLaFerla, Godfrey-
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