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https://www.um.edu.mt/library/oar/handle/123456789/5669
Title: | The efficacy of lymph node fine needle aspiration cytology |
Authors: | Attard, Jason Galea, Jonathan Betts, Alexandra |
Keywords: | Lymph nodes Cytology Needle biopsy |
Issue Date: | 2015 |
Publisher: | Malta Medical Journal |
Citation: | Malta Medical Journal. 2015, Vol. 27(3), p. 16-21 |
Abstract: | Fine needle aspiration cytology (FNAC) of lymph nodes is a safe, easy, cheap and quick diagnostic tool, which involves the examination of a random sample of cells from a lymph node. To assess the distribution of diagnostic categories and the efficacy of lymph node fine needle aspiration cytology at our institution. These were compared to the literature. Methodology: All of lymph node FNAC cases taken between the 1st January 2012 and the 31st December 2013 were retrieved from our Laboratory Information System. A total of 300 cases were retrieved and then placed into one of six categories; Category 1: Non-diagnostic, 2: Reactive, 3: Probably reactive but lymphoma cannot be excluded, 4: Non-Hodgkin lymphoma, 5: Hodgkin lymphoma, and 6: Metastasis. These were then correlated with the histology of the lymph node excision specimens. The proportion of diagnoses placed under categories 1, 2, 3, 4, 5 and 6 represent 14%, 53%, 4.3%, 5.7%, 1.7% and 21.3% of the total respectively. The overall efficacy of FNAC showed a sensitivity of 84.5%, specificity of 99.3%, a false negative rate of 10%, a false positive rate of 0.7%, accuracy of 93.1%, positive predictive value of 98.8% and negative predictive value of 89.9%. FNAC of lymph nodes is a very useful and effective tool in triaging patients with lymphadenopathy. |
URI: | https://www.um.edu.mt/library/oar//handle/123456789/5669 |
Appears in Collections: | MMJ, Volume 27, Issue 3 MMJ, Volume 27, Issue 3 Scholarly Works - FacM&SPat |
Files in This Item:
File | Description | Size | Format | |
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The efficacy of lymph node fine needle.pdf | 1.2 MB | Adobe PDF | View/Open |
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