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dc.contributor.authorChetcuti, Sarah-
dc.contributor.authorSammut, Enya-
dc.contributor.authorSammut, Melissa-
dc.contributor.authorCalleja-Agius, Jean-
dc.identifier.citationChetcuti, S., Sammut, E., Sammut, M., & Calleja-Agius, J. (2019). The other face of oxytocin : role of oxytocin in neuropsychiatric disorders. International Journal of Prenatal & Life Sciences, 3(3), 10.24946/IJPLS.en_GB
dc.description.abstractThe neuropeptide oxytocin (OXT) is well-known for its role in pregnancy and lactation. However, its role extends beyond the reproductive system. In fact, the role of OXT in neuropsychiatric disorders has long been studied. OXT is largely associated with social behavior and stress reduction, and so it is to no surprise that it is thought to be involved in the pathophysiology of neuropsychiatric disorders. Many studies have investigated how abnormalities in the OXT system give rise to symptoms and socio-cognitive deficits many patients with neuropsychiatric disorders exhibit. Understanding the patho-physiology of these disorders enables the development of more efficacious therapeutic agents which target the abnormalities and give rise to less adverse effects. In this review we summarize the literature available to date about the role of OXT in schizophrenia, autism spectrum disorders (ASD), addiction to drugs of abuse and anorexia nervosa (AN). Although these disorders are very Sept.arate and different entities, they all have something common in their pathology; they are associated with deranged OXT systems. Although many studies have been conducted to determine the exact role of OXT in these disorders and how OXT can be used to treat these disorders, research is still in its infancy. Further research is required to be able to standardize OXT as a therapeutic agent, determine its effects and safety, both in short-term and long-term use.en_GB
dc.subjectAnorexia nervosaen_GB
dc.subjectSubstance abuseen_GB
dc.titleThe other face of oxytocin : role of oxytocin in neuropsychiatric disordersen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.publication.titleInternational Journal of Prenatal & Life Sciencesen_GB
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