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|Title:||Malignant disease in childhood : the price of cure : late physical and socioeconomic effects of treatment|
|Authors:||Attard Montalto, Simon|
Torpiano, John G.
|Keywords:||Cancer in children -- Treatment -- Complications|
Cancer in children -- Psychological aspects
Neoplasms -- Infancy and childhood
|Publisher:||Maltese Medical Journal|
|Citation:||Maltese Medical Journal. 1997, Vol. 9(2), p. 20-25|
|Abstract:||The aim of cancer therapy in childhood is to achieve a lasting cure without physical and psychosocial harm and, preferably, at a low financial cost. Although cure is possible in many types of childhood cancer, this is often accompanied by complications as a consequence of intensive therapy. These late effects primarily affect fertility, the cardio-respiratory and endocrinological systems. Psychosocial adverse effects may have serious implications on the marriage and employment prospects of those patients surviving into adulthood. Furthermore, the risk of treatment-induced, secondary malignancies may increase as survival improves. With current intensive chemotherapy and radiotherapy, the attainment of cure rates in (EXC)ess of 60-70% is, inevitably, associated with significant morbidity. Indeed, recent developments in cancer therapy have focused on ways of reducing this morbidity, whilst still maintaining the overall improvement in survival.|
|Appears in Collections:||MMJ, Volume 9, Issue 2|
MMJ, Volume 9, Issue 2
Scholarly Works - FacM&SPae
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