Please use this identifier to cite or link to this item:
Title: New gold standard treatment for acute stroke : endovascular thrombectomy using stentretrievers
Other Titles: Editorial [Malta Medical Journal, Vol.27(4)]
Authors: Pullicino, Patrick
Cordina, Steve M.
Keywords: Stroke, Acute
Heart -- Diseases -- Treatment
Endovascular techniques
Endovascular procedures
Blood vessels -- Endoscopic surgery
Issue Date: 2015
Publisher: Malta Medical Journal
Citation: Malta Medical Journal. 2015, Vol. 27(4), p. 1-3
Abstract: The last year has seen the most dramatic advance in the treatment of acute stroke since the United States National Institutes of Health tissue plasminogen activator (tPA) study showed in 1995 that intravenous (IV) thrombolysis delivered within three hours of stroke onset could improve outcome. IV tPA became standard treatment for acute stroke after that study, but there was still difficulty in recanalising large vessel occlusions and up to one half of patients were left with severe deficits despite IV tPA. In 2008, the European Cooperative Acute Stroke Study (ECASS) III extended the IV tPA time window from three to four and a half hours from stroke onset but favourable outcome at 90 days was still only seen in 52% of patients, as in other studies. In cardiology, it was demonstrated that endovascular treatments were superior to IV, but it appeared that this was going to be one area where stroke differed. Repeated endovascular studies, the largest of which was Interventional Management of Stroke (IMS) III trial showed no advantage over IV tPA. The only exception was the borderline results of the Prolyse in Acute Thromboembolism (PROACT) II trial in 1999. One common recurring theme was the need for early recanalization for maximal benefit and the decreased recanalization noted with larger clot burden.
Appears in Collections:MMJ, Volume 27, Issue 4
MMJ, Volume 27, Issue 4

Files in This Item:
File Description SizeFormat 
Editorial MMJ 27-4.pdf162.78 kBAdobe PDFView/Open

Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.