Neurogenic disturbances of cardiac rhythm

Abstract

Arrhythmias are disturbances of electrical activation of the heart and are commonly encountered clinical conditions. Although typically associated with cardiac pathology, they have also been described in stroke and epilepsy. Two closely related structures, the insula and the temporal lobe, particularly the mesial region, have been implicated. Derangement of central autonomic control appears to be a key driver in neurogenic arrhythmogenesis and both these structures appear to play some role in influencing autonomic activity. Our understanding of this phenomenon is only in its infancy, and more research will be necessary to further it.