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https://www.um.edu.mt/library/oar/handle/123456789/103508| Title: | Between-batch variation of calibrator activity can significantly influence fluorogenic measurement of thrombin generation |
| Authors: | Van Veen, Joost J. Gatt, Alexander Cooper, P. C. Kitchen, S. Makris, M. |
| Keywords: | Thrombin -- Physiological effect Fluorescent dyes -- Diagnostic use Thrombosis -- Diagnosis |
| Issue Date: | 2006 |
| Publisher: | Wiley |
| Citation: | Van Veen, J. J., Gatt, A., Cooper, P. C., Kitchen, S., & Makris, M. (2006). Between‐batch variation of calibrator activity can significantly influence fluorogenic measurement of thrombin generation. Journal of Thrombosis and Haemostasis, 4(11), 2514-2516. |
| Abstract: | There is increasing interest in thrombin generation, and the endogenous thrombin potential (ETP) may have a closer relationship with a clinical phenotype of bleeding or thrombosis than traditional laboratory tests. The fluorogenic calibrated automated thrombin generation test with dedicated software (Synapse B.V.,Maastricht, TheNetherlands) calculates thrombin generation of a sample by comparing fluorescent activity in the test sample with the fluorescent activity of a non-clotting calibrator with a known concentration of thrombin activity measured in parallel. [Excerpt] |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/103508 |
| Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Between batch variation of calibrator activity can significantly influence fluorogenic measurement of thrombin generation 2006.pdf Restricted Access | 114.43 kB | Adobe PDF | View/Open Request a copy |
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