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https://www.um.edu.mt/library/oar/handle/123456789/104206| Title: | The effect of calcitriol on the expression of interferon signature genes in dendritic cells and macrophages in systemic lupus erythematosus |
| Other Titles: | P234 The effect of calcitriol on the expression of interferon signature genes in dendritic cells and macrophages in systemic lupus erythematosus |
| Authors: | Magro, Rosalie Seria, Elisa Grech, Godfrey Borg, Andrew A. Scerri, Christian A. |
| Keywords: | Systemic lupus erythematosus -- Case studies Vitamin D -- Health aspects Calcitriol Dendritic cells -- Physiology Macrophages -- Physiology |
| Issue Date: | 2022 |
| Publisher: | Oxford Academic |
| Citation: | Magro, R., Seria, E., Grech, G., Borg, A. A., & Scerri, C. (2022). P234 The effect of calcitriol on the expression of interferon signature genes in dendritic cells and macrophages in systemic lupus erythematosus. Rheumatology, 61(Suppl. 1), keac133.233. |
| Abstract: | Background/Aims: A number of studies have demonstrated the inverse association between vitamin D and (i) disease activity and (ii) interferon (IFN) signature gene expression in systemic lupus erythematosus (SLE). The aim of the study was to establish the effect of calcitriol supplementation to cultured macrophages and dendritic cells (DC) from a SLE patient and control, on the expression of 12 IFN signature genes, interferon regulatory factor (IRF)7 and IRF8. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/104206 |
| Appears in Collections: | Scholarly Works - FacM&SPat |
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|---|---|---|---|---|
| The effect of calcitriol on the expression of interferon signature genes in dendritic cells and macrophages in systemic lupus erythematosus 2022.pdf Restricted Access | 58.87 kB | Adobe PDF | View/Open Request a copy |
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