Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/108907| Title: | CIP2A expression is upregulated in triple-negative breast cancer |
| Authors: | Baldacchino, Shawn Wastall, Laura Saliba, Christian Hughes, Thomas A. Speirs, Valerie Grech, Godfrey |
| Keywords: | Triple negative breast neoplasms Breast -- Cancer -- Treatment Biochemical markers -- Diagnostic use Protein phosphatase 2 Phosphoprotein phosphatases -- Inhibitors |
| Issue Date: | 2015 |
| Publisher: | University of Malta. Medical School |
| Citation: | Baldacchino, S., Wastall, L., Saliba, C., Hughes, T.A., Speirs, V., & Grech, G. (2015). CIP2A expression is upregulated in triple-negative breast cancer. IX Malta Medical School Conference abstract book, OP3.14. |
| Abstract: | Introduction: Expression of cancerous inhibitor of protein phosphatase 2A (CIP2A) has been correlated with the clinical aggression and progression of breast cancer. CIP2A inhibits protein phosphatase 2A promoting proliferation and survival. This study aims to compare the transcript and protein expression in triple negative breast cancer (TNBC) and determine the signifìcance of CIP2A localisation using formalin fìxed paraffin embedded (FFPE) breast cancer tissue. Breast cancers with increased CIP2A are potential candidates for novel PP2A activation therapy. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/108907 |
| ISSN: | 18133339 |
| Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| CIP2A expression is upregulated in triple negative breast cancer 2015.pdf | 185.55 kB | Adobe PDF | View/Open |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.