Patients’ quality of life after bipolar transurethral enucleation and laparoscopic simple prostatectomy for large benign prostatic hyperplasia : quality of life after surgical treatment of large BPH

Abstract

BACKGROUND: The purpose of this study was to assess the changes in storage, voiding, and post-micturition LUTS and disease-related QoL in patients with large benign prostatic hyperplasia (BPH) who underwent either bipolar transurethral enucleation (B-TUEP) or laparoscopic simple prostatectomy (LSP).

METHODS: This was a prospective study, involving 112 men, aged 58 -78, with BPH > 80m/L, of whom 55 were treated through B-TUEP and 57 through LSP.

RESULTS: Both patient groups experienced a significant reduction in LUTS (p < 0.001 for all); however, the LSP patients had a higher reduction in storage, voiding, and post-micturition symptoms (p < 0.001 for all comparisons). Overall, LUTS decreased by 76±5.8% in the LSP group and by 70±7.8% in the B-TUEP group. The percentage improvement in QoL was 61.66±15.74% in the LSP group versus 52.69±17.85% in the B-TUEP group, p = 0.006. There was a significant association between reduction in LUTS and improvement in disease-related QoL (rs =- 0.463, 95% CI: -0.293 to -0.605). The advantages of B-TUEP were shorter operative duration, hospital stay, and catheter duration (p < 0.001).

CONCLUSIONS: Our results suggest that both B-TUEP and LSP are effective surgical treatments for patients with BPH > 80m/L, which contribute to significant reductions in LUTS and improved QoL. Yet, the extent of improvement was greater in the LSP group, whereas B-TUEP required less operative time, hospital stay, and catheter duration.