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Title: Inflammation and insulin resistance : evolution, pathology and therapy
Authors: Pace, Nikolai Paul
Keywords: Insulin resistance
Issue Date: 2014
Publisher: Medical Portals Ltd.
Citation: Pace, N.P. (2014). Inflammation and insulin resistance : evolution, pathology and therapy. The Synapse, 13(4), 16-17
Abstract: Chronic low-level subclinical inflammation is an established risk factor in the development of insulin resistance, endothelial damage and atherosclerosis. The obesity-associated insulin resistance in adipose, liver and muscle tissue is promoted by a switch in macrophage activation driven by transcription factors that play crucial roles in innate immunity. This review discusses the evolutionary link between body defense mechanisms and insulin resistance.
Appears in Collections:Scholarly Works - FacM&SAna
The Synapse, Volume 13, Issue 4
The Synapse, Volume 13, Issue 4

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