Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/14272| Title: | The dark matter of the genome : some insights and clinical applications |
| Authors: | Grech, Alfred Balzan, Michael |
| Keywords: | Human genome Genomics RNA |
| Issue Date: | 2016 |
| Publisher: | Medical Portals Ltd. |
| Citation: | Grech, A. & Balzan, M. (2016). The dark matter of the genome : some insights and clinical applications. The Synapse, 15(3), 7-9 |
| Abstract: | Only approximately 1.5% of the human genome encodes protein sequence; the rest is ‘dark matter’. Research on these noncoding regions shows that they play roles in cellular homeostasis, development, differentiation and metabolism. Cancer, cardiovascular, developmental, and neurological diseases are characterised by aberrant expression of these regions. Exploring their clinical utility as biomarkers and molecular targets in medical theranostics is a very promising way forward. |
| URI: | https://www.um.edu.mt/library/oar//handle/123456789/14272 |
| Appears in Collections: | The Synapse, Volume 15, Issue 3 The Synapse, Volume 15, Issue 3 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| The dark matter of the genome.pdf | 2.33 MB | Adobe PDF | View/Open |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.