Progress and insights in health and biomedical research

Abstract

On behalf of the Editorial Team of Scientific Letters, we are pleased to announce the publication of the journal’s fourth issue. In 2025, Scientific Letters continued its mission of disseminating high-quality open-access research across the fields of biology and medicine. The two review articles and five original research papers published this year highlight both foundational biological mechanisms and pressing clinical and public health issues. João Carvalho et al. performed a systematic integrative review addressing different orthodontic approaches to the traction of impacted canines. Their work critically analyzed existing techniques, highlighting the advantages and limitations of surgical and orthodontic strategies, and emphasizing the importance of individualized treatment planning to optimize functional and esthetic outcomes. This review contributes valuable guidance for clinical decision-making in orthodontic practice.