Effects of Magnetrex® – Magnesium, Taurine, Citrus sinensis and Vitamin B6 – on muscle cramps and anxiety in an adult population : a retrospective chart review

Abstract

INTRODUCTION: The development of effective interventions, including pharmacotherapy and dietary supplements, to alleviate symptoms of stress, anxiety, and related physiological discomfort such as cramps has gained considerable interest in recent years. In this context, several components like magnesium, taurine, Citrus sinensis, and vitamin B6 have individually shown promising effects on stress reduction, anxiety management and associated cramp reduction.

OBJECTIVES: To evaluate the potential effects of supplementation with Magnetrex® (Surveal Pharma), a combination of magnesium, taurine, Citrus sinensis, and vitamin B6, on signs and symptoms of stress and anxiety in adults as well as muscle cramps.

METHODS: A retrospective chart review design was employed among adults in Malta initiated on Magnetrex®. Data were extracted from medical records and Perceived Stress Scale (PSS) and Hamilton Anxiety Rating Scale (HAM-A) scales which were used to assess stress and anxiety symptoms, respectively, at baseline and at four-month follow-up. Changes in stress symptoms, anxiety, and muscle cramps were analyzed, and linear mixed models adjusted for relevant covariates were performed to test changes in PSS and HAM-A scales from baseline to follow-up.

RESULTS: This study included 57 subjects who initiated Magnetrex® supplementation. Our results showed significant improvements in various stress symptoms and a significant decrease in the PSS and HAM-A scales, indicating lower levels of stress and less severity of anxiety symptoms after four months of Magnetrex® supplementation. Improvement in muscle cramps was also reported.

CONCLUSIONS: The results of this study suggest that supplementation with Magnetrex® may be effective in improving mental conditions such as stress and anxiety, and in reducing muscle cramps.