Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/144028
Title: Non-coding RNA-based therapy
Authors: Grech, Alfred
West, Stephen
Keywords: RNA -- Therapeutic use
RNA, untranslated
Catalytic RNA
Oligonucleotides, antisense
Issue Date: 2022
Publisher: Medical Portals Ltd
Citation: Grech, A., & West, S. (2022). Non-coding RNA-based therapy. The Synapse : the Medical Professionals' Network, 21(3), 18-20.
Abstract: In recent years, some of the physiological and pathophysiological roles of non-coding RNAs (ncRNAs) have been discovered. These discoveries have been pivotal in providing insight on the basis of various diseases where ncRNAs are aberrantly expressed. Moreover, they are being studied in translational research to use these mechanisms for ‘non-coding RNA based therapy’. The main players being investigated in non-coding RNA-based therapies include antisense oligonucleotides, locked nucleic acid anti-miRs, miRNA sponges, miRNA mimics, siRNAs and ribozymes.
URI: https://www.um.edu.mt/library/oar/handle/123456789/144028
Appears in Collections:The Synapse, Volume 21, Issue 3

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