Multiple problems in siblings with Gardner’s syndrome

Abstract

The problems encountered in the diagnosis of two siblings suffering from a high penetration variant of Gardner’s syndrome are presented. The importance of recognizing the extra colonic manifestations of the syndrome at an early stage and technical difficulties encountered during colonoscopy are noted. Operative procedures available to treat multiple colonic polyps in Gardner’s syndrome are discussed in relation to technical problems which may be encountered in the individual case. Hopefully this presentation will highlight the importance of the setting up of a Familial Polyposis Coli register in Malta in order to facilitate early diagnoses and treatment of the condition.