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Title: Emphysema : the challenge of the remodelled lung
Authors: Blundell, Renald
Harrison, David J.
Wallace, W. A. H.
Keywords: Emphysema, Pulmonary
Lungs -- Diseases, Obstructive
Gene therapy
Issue Date: 2004
Publisher: John Wiley & Sons, Ltd.
Citation: Blundell, R., Harrison, D. J., & Wallace, W. A. H. (2004). Emphysema: the challenge of the remodelled lung. The Journal of Pathology, 202(2), 141-144.
Abstract: Emphysema is recognized as the component of chronic obstructive airways disease that is responsible for airways obstruction. Different patterns of emphysema are, however, recognized, suggesting possible different pathogenetic processes within the lung. This, coupled with the associated idea of susceptibility factors to the development of emphysema, has led to studies of genes that may be involved in the defence of the lung from proteolytic and oxidative damage. These studies have been driven by the goal of finding a treatment for emphysema, but appear to have lost sight of the fundamental remodelling of the lung that has occurred in patients with emphysema and the fact that it is not a single morphological entity.
Appears in Collections:Scholarly Works - FacM&SPB

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