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https://www.um.edu.mt/library/oar/handle/123456789/23179| Title: | Method development studies on the HPLC analysis of candesartan cilexetil using a core-shell column |
| Authors: | Farrugia, Maria Sinagra, Emmanuel Farrugia, Claude |
| Keywords: | High performance liquid chromatography |
| Issue Date: | 2012 |
| Publisher: | University of Malta. Department of Chemistry |
| Citation: | Farrugia, M., Azzopardi, A., & Farrugia, C. (2012). Method development studies on the HPLC analysis of candesartan cilexetil using a core-shell column. Seventh National Chemistry Symposium, Department of Chemistry, University of Malta, Malta. |
| Abstract: | Advances in High Performance Liquid Chromatography (HPLC) have led to increased sample throughput and productivity in pharmaceutical analysis. Recently developed core-shell columns consist of a porous shell and a solid silica core. Thus the mobile phase is only allowed to flow along the porous shell of the particles, decreasing backpressures whilst increasing efficiency. The objective of this study was to use such column technology to minimize the elution time of the drug candesartan cilexetil and its impurities, whilst improving resolution and selectivity. |
| URI: | https://www.um.edu.mt/library/oar//handle/123456789/23179 |
| Appears in Collections: | Scholarly Works - FacSciChe Scholarly Works - JCChe |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Poster16.pdf | 333.01 kB | Adobe PDF | View/Open |
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