Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/24645
Title: A new two steps synthesis of α-substituted γ-methyl γ-lactones from nitroalkanes
Authors: Ballini, Roberto
Bosica, Giovanna
Keywords: Nitroalkanes -- Synthesis
Chemistry, Analytic
Issue Date: 1996
Publisher: Georg Thieme Verlag
Citation: Ballini, R., & Bosica, G. (1996). A new two steps synthesis of α-substituted γ-methyl γ-lactones from nitroalkanes. Synlett, 11, 1115-1116.
Abstract: α-Substituted γ-methyl γ-lactones are efficiently prepared, in two steps, by regiospecific Michael addition of nitroalkanes to methyl trans-4-oxo-2-pentenoate in MeCN/DBU followed by chemoselective reduction of the obtained enones with NiCl2⋅6H2O/NaBH4. By this method a variety of functionalized 3,5-disubstituted butyrolactones can be obtained.
URI: https://www.um.edu.mt/library/oar//handle/123456789/24645
Appears in Collections:Scholarly Works - FacSciChe

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