α-Nitrocycloalkanones as a source of α,ω-dicarboxylic acid dimethyl esters

Abstract

α,ω-Dicarboxylic acid dimethyl esters are casily obtained by ring cleavage of α-nitrocycloalkanones. Thus, reaction of the latter compounds with three equivalents of potassium persulfate, in methanol and in presence of sulfuric acid at 80°C, provides α,ω-dicarboxylic acid dimethyl esters in high yields. Long-chain, and alkylated α,ω-dicarboxylic acid dimethyl esters can be also efficiently obtained.