Furosemide-induced eruption of haemorrhagic bullae on the fingers

Abstract

This article describes a man who developed severe haemorrhagic necrotizing blisters within 1 week of being started on regular furosemide. The lesions were confined to the fingers bilaterally and accompanied by severe swelling and loss of function. There were no associated features. All investigations were negative and an adverse drug reaction to furosemide was diagnosed. The drug was stopped and the lesions resolved fully. This form of cutaneous drug reaction is one of the rarest forms of reactions to furosemide especially when confined only to the fingers. One must be aware of such complications and be prepared to withdraw the diuretic to confirm the diagnosis and achieve resolution of the lesions.