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https://www.um.edu.mt/library/oar/handle/123456789/48659| Title: | Prevalence of the CYP2C19 *2 allele in Maltese patients on clopidogrel therapy |
| Authors: | Wirth, Francesca Zahra, Graziella Xuereb, Robert G. Barbara, Christopher Fenech, Albert Azzopardi, Lilian M. |
| Keywords: | Coronary heart disease -- Malta -- Case studies Coronary heart disease -- Treatment Coronary heart disease -- Chemotherapy Clopidogrel |
| Issue Date: | 2015-09 |
| Publisher: | University of Malta. Department of Pharmacy |
| Citation: | Wirth, F., Zahra, G., Xuereb, R. G., Barbara, C., Fenech, A., & Azzopardi, L. M. (2015, September). Prevalence of the CYP2C19 *2 allele in Maltese patients on clopidogrel therapy. Poster session presented at the FIP 75th World Congress of Pharmacy and Pharmaceutical Sciences, Düsseldorf, Germany. |
| Abstract: | A poster presentation regarding the prevalence of the CYP2C19 *2 allele in Maltese patients on clopidogrel therapy. Background: The CYP2C19 loss-of-function (LoF) *2 allele is associated with reduced CYP2C19 activity which impairs clopidogrel bioactivation and increases the risk of adverse cardiac outcomes after percutaneous coronary intervention (PCI). To-date, prevalence of the CYP2C19 *2 allele in the Maltese population has not been reported. Aims: To genotype Maltese patients undergoing PCI for the CYP2C19 *2 allele and to compare prevalence of the *2 allele in this Maltese population to other populations bordering the Mediterranean Sea. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/48659 |
| Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Prevalence_of_the_CYP2C19_2_allele_in_Maltese_patients_on_clopidogrel_therapy_on_clopidogrel_therapy_2015.pdf | 466.34 kB | Adobe PDF | View/Open |
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