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https://www.um.edu.mt/library/oar/handle/123456789/49459| Title: | A simple method for the determination of water content in tetrahydrofuran |
| Authors: | Xiberras, Maria Attard, Everaldo Sammut Bartolo, Nicolette Serracino-Inglott, Anthony |
| Keywords: | Tetrahydrofuran -- Analysis Tetrahydrofuran -- Water content Karl Fischer technique Solvents -- Analysis Spectrum analysis |
| Issue Date: | 2019-09 |
| Publisher: | University of Malta. Department of Pharmacy |
| Citation: | Xiberras, M., Attard, E., Sammut Bartolo, N., & Serracino-Inglott, A. (2019, September). A simple method for the determination of water content in tetrahydrofuran. Poster session presented at the FIP World Congress of Pharmacy and Pharmaceutical Sciences, Abu Dhabi, United Arab Emirates. |
| Abstract: | A poster presentation regarding a simple method for the determination of water content in tetrahydrofuran. Introduction: Water content in organic solvents used for chemical synthesis frequently influences the reaction outcome and yield. Water content in solvents is usually determined using a Karl Fischer titration and azeotropic distillation. Both methods have limitations, the Karl Fischer apparatus is easily disturbed while the azeotropic distillation is complicated to conduct, time consuming and has a low precision in reading the volume of water collected. Aim: To develop a simple method to determine the water content in tetrahydrofuran THF using UV/Vis spectroscopy with cobalt chloride (CoCl2). |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/49459 |
| Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| A_simple_method_for_the_determination_of_water_content_in_tetrahydrofuran_2019.pdf | 279.25 kB | Adobe PDF | View/Open |
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