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https://www.um.edu.mt/library/oar/handle/123456789/49680| Title: | LC-HRMS analysis of a green steroid orthoesterification reaction |
| Authors: | Sammut Bartolo, Nicolette Zoidis, Grigoris Gikas, Evangelos Ferrito, Victor Serracino-Inglott, Anthony |
| Keywords: | High performance liquid chromatography High resolution spectroscopy Green chemistry Acetonitrile |
| Issue Date: | 2018-03 |
| Publisher: | University of Malta. Department of Pharmacy |
| Citation: | Sammut Bartolo, N., Zoidis, G., Gikas, E., Ferrito, V., & Serracino-Inglott, A. (2018, March). LC-HRMS analysis of a green steroid orthoesterification reaction. Poster session presented at the 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain. |
| Abstract: | A poster presentation regarding LC-HRMS analysis of a green steroid orthoesterification reaction. Introduction: A reaction between a 17α,21-hydroxy steroid and the appropriate orthoester using acid catalysis, was carried out using green chemistry principles, to synthesize the corresponding 17α,21-steroid orthoester (Figure 1). Aims: To develop an LC-HRMS method for the separation and identification of orthoesterification reaction products and to establish whether the desired 17α,21-steroid orthoester was obtained. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/49680 |
| Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| LC_HRMS_analysis_of_a_green_steroid_orthoesterification_reaction_2018.pdf | 1.53 MB | Adobe PDF | View/Open |
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