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Title: Gastric acid control, amylase activity and proton pump inhibitors
Authors: Galea, Charlene
Azzopardi, Lilian M.
Serracino-Inglott, Anthony
LaFerla, Godfrey
Keywords: Amylases
Proton pump inhibitors -- Therapeutic use
Gastric juice -- Analysis
Stomach -- Diseases -- Diagnosis
Issue Date: 2013-08
Publisher: University of Malta. Department of Pharmacy
Citation: Galea, C., Azzopardi, L. M., Serracino-Inglott, A., & LaFerla, G. (2013, August). Gastric acid control, amylase activity and proton pump inhibitors. Poster session presented at the International Pharmaceutical Federation (FIP) World Congress, Dublin, Ireland.
Abstract: A poster presentation regarding gastric acid control, amylase activity and proton pump inhibitors. Introduction: Proton pump inhibitors increase gastric pH to ensure healing of duodenal and gastric ulcers. However, this increased pH is also the optimal pH for salivary (S-AM) and pancreatic amylase (P-AM) activity in gastric juice. Could a high amylase level in gastric juice explain dyspepsia in patients who fail to respond to standard PPI treatment?. Aims: • To quantify total (AMYL) and pancreatic active amylase present in gastric juice samples. • To correlate any relevant patient and drug history with the gastric amylase activity.
Appears in Collections:Scholarly Works - FacM&SPha

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