Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/50639| Title: | SLCO1B1 genetic polymorphisms in cardiac patients on simvastatin |
| Authors: | Cerdá Iñesta, Judith Wirth, Francesca Zahra, Graziella Xuereb, Robert G. Barbara, Christopher Serracino-Inglott, Anthony |
| Keywords: | Genetic polymorphisms Heart -- Diseases -- Patients Muscles -- Diseases Simvastatin Cardiovascular agents Pharmacogenetics |
| Issue Date: | 2018-09 |
| Publisher: | University of Malta. Department of Pharmacy |
| Citation: | Cerdá Iñesta, J., Wirth, F., Zahra, G., Xuereb, R. G., Barbara, C., & Serracino-Inglott, A. (2018, September). SLCO1B1 genetic polymorphisms in cardiac patients on simvastatin. Poster session presented at the 78th FIP World Congress of Pharmacy and Pharmaceutical Sciences, Glasgow, United Kingdom. |
| Abstract: | A poster presentation regarding SLCO1B1 genetic polymorphisms in cardiac patients on simvastatin. Introduction: The SLCO1B1 rs4149056 c.521T>C gene variant is associated with higher serum simvastatin concentrations and increased risk of simvastatin-induced myopathy. Aim: To classify a cohort of cardiac patients on simvastatin according to SLCO1B1 genotype, SLCO1B1 function and myopathy risk. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/50639 |
| Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| SLCO1B1_genetic_polymorphisms_in_cardiac_patients_on_simvastatin_2018.pdf | 1.25 MB | Adobe PDF | View/Open |
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