Please use this identifier to cite or link to this item:
Title: Swollen limbs and bone pain : a case report
Authors: Sammut, David
Debono, Miguel
Cacciottolo, Joseph M.
Keywords: ACTH -- Malta -- Case studies
Cushing's syndrome
Paraneoplastic syndromes
Issue Date: 2005
Publisher: Malta Medical Journal
Citation: Malta Medical Journal. 2005, Vol.17(2), p. 40-45
Abstract: A 50 year old man presented with peripheral oedema, abdominal distension and a pulmonary opacity on CXR. He subsequently perforated his sigmoid colon as a complication of diverticulitis with pericolic abscess. After colectomy his postoperative period was marked by severe hypokalaemia, metabolic alkalosis, hyperglycaemia and recurrent chest infections. Paraneoplastic Cushing's syndrome was diagnosed after finding elevated serum cortisol and ACTH levels. CT-guided biopsy of the lung lesion revealed small-cell carcinoma. Bone scan disclosed collapse of numerous thoracic vertebrae possibly due to osteoporosis or oncogenic osteomalacia. Treatment with steroid-synthesis blockers was commenced but the patient died before tumour-directed therapy could be started. Ectopic ACTH syndrome and oncogenic osteomalacia are discussed.
Appears in Collections:MMJ, Volume 17, Issue 2
MMJ, Volume 17, Issue 2
Scholarly Works - FacM&SMed

Files in This Item:
File Description SizeFormat 
2005.Vol17.Issue2.A8.pdfSwollen limbs and bone pain: a case report122.33 kBAdobe PDFView/Open

Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.