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Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/59567
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dc.contributor.authorZammit, Martha Anne-
dc.contributor.authorAgius, Stefanie Marie-
dc.contributor.authorCalleja-Agius, Jean-
dc.date.accessioned2020-08-18T09:11:57Z-
dc.date.available2020-08-18T09:11:57Z-
dc.date.issued2017-
dc.identifier.citationZammit, M. A., Agius, S. M., & Calleja-Agius, J. (2017). Transient neonatal diabetes mellitus : a challenge and opportunity for specialized nursing care. Neonatal Network, 36(4), 196-205.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/59567-
dc.description.abstractTransient neonatal diabetes mellitus (TNDM) is a rare disorder, with a reported incidence of approximately 1 in 450,000 live births. It is characterized by insulin-requiring hyperglycemia in the neonatal period. The disease improves by early childhood, but the patient may relapse in later life. Diagnosis is made after genetic testing following presentation with hyperglycemia not conforming to Type 1 or Type 2 diabetes. Management is based on insulin and possible sulfonylurea administration. Three genetically distinct subtypes of TNDM are recognized. Type 1 TNDM is due to overexpression of genes at the 6q24 locus, whereas the 11p15 locus is involved in Type 2 and 3 TNDM. In this article the clinical presentation, management, and genetics of TNDM are discussed, particularly emphasizing the role of the neonatal nurse.en_GB
dc.language.isoenen_GB
dc.publisherSpringer Publishing Companyen_GB
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_GB
dc.subjectDiabetes in childrenen_GB
dc.subjectHyperglycemiaen_GB
dc.subjectHypoglycemiaen_GB
dc.subjectHuman chromosome abnormalities -- Diagnosisen_GB
dc.subjectInsulinen_GB
dc.subjectSulfonylureasen_GB
dc.subjectDiabetes -- Genetic aspectsen_GB
dc.titleTransient neonatal diabetes mellitus : a challenge and opportunity for specialized nursing careen_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.description.reviewedpeer-revieweden_GB
dc.identifier.doi10.1891/0730-0832.36.4.196-
dc.publication.titleNeonatal Networken_GB
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