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DC Field | Value | Language |
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dc.contributor.author | Parascandalo, Raymond | - |
dc.contributor.author | Felice, Alex | - |
dc.contributor.author | Rizzo, M. | - |
dc.contributor.author | Vassallo Agius, Paul | - |
dc.date.accessioned | 2014-12-17T18:49:50Z | - |
dc.date.available | 2014-12-17T18:49:50Z | - |
dc.date.issued | 1996 | - |
dc.identifier.citation | Maltese Medical Journal. 1996, Vol. 8(2), p. 29-31 | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar//handle/123456789/718 | - |
dc.description.abstract | Routine screening for congenital hypothyroidism (CHT) has been introduced because clinical features of CHT may not be evident before the baby is a few weeks old and treatment at this stage may already be too late. Since a newborn testing programme employing liquid cord blood for other conditions had already been developed in the University of Malta and the Department of Health, we explored the possibility of implementing newborn thyroid testing using liquid cord blood. A similar programme had been implemented successfully in Finland and Philadelphia. Between September 1989 and August 1995 around 32,000 newborns were tested. This is nearly complete ascertainment. Preliminary testing was by radioimmunoassay for TSH. The sera of those with TSH levels more than 13mU/l were further tested for free T4. If the free T4 level was below 12 pmol/l, the babies were recalled for clinical evaluation and repeat testing. Other babies were recalled for technical reasons, giving a total recall rate of 3.88%. CHT was identified in seven newborns and treatment started within 3 weeks of delivery. One baby was reported normal on screening but was suspected to have CHT on clinical grounds at 3 weeks of age, confirmed biochemically. The incidence of CHT in Malta is therefore 1 in 4500. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Maltese Medical Journal | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Congenital hypothyroidism -- Diagnosis | en_GB |
dc.subject | Congenital hypothyroidism -- Malta -- Statistics | en_GB |
dc.subject | Hypothyroidism -- Congenital | en_GB |
dc.title | Screening for congenital hypothyroidism in Maltese newborns using cord blood | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | - |
Appears in Collections: | MMJ, Volume 8, Issue 2 MMJ, Volume 8, Issue 2 Scholarly Works - FacM&SPae Scholarly Works - FacM&SPB |
Files in This Item:
File | Description | Size | Format | |
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mmj080229.pdf | 5.09 MB | Adobe PDF | View/Open |
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