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Title: Cancer epigenetics and its clinical applications
Authors: Grech, Alfred
Balzan, Michael
Keywords: Epigenetics
Cancer -- Genetic aspects
Cancer -- Treatment
DNA -- Methylation
Issue Date: 2020
Publisher: Medical Portals Ltd.
Citation: Grech, A., & Balzan, M. (2020). Cancer epigenetics and its clinical applications. The Synapse : the Medical Professionals' Network, 19(5), 8-9.
Abstract: Epigenetics is defined as 'somatically inheritable changes that are not accompanied by alterations in DNA sequence'. DNA methylation, histone modifications and non-coding RNAs are all epigenetic mechanisms. Epigenetic aberrations (or epimutations) have been found to be responsible for carcinogenesis. The research of these epimutations is providing a platform for their application in cancer diagnosis, prognosis and therapeutics.
Appears in Collections:The Synapse, Volume 19, Issue 5
The Synapse, Volume 19, Issue 5

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