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https://www.um.edu.mt/library/oar/handle/123456789/82318| Title: | Globin gene organisation and expression |
| Authors: | Zhao, J. Chui, D. H. K. Felice, Alex |
| Keywords: | Hemoglobin Hemoglobinopathy Sickle cell anemia Molecular microbiology |
| Issue Date: | 1987 |
| Publisher: | American Society of Hematology |
| Citation: | Zhao, J., Chui, D. H. K., & Felice, A. (1987). Globin gene organisation and expression. Twenty-ninth Annual Meeting of the American Society of Hematology, Washington, DC. 82a. |
| Abstract: | Re-arranqement of the α and ζ qlobin qenea are rather common in Black Americans. Two variants of the -3.7 Kb α qlobin qene deletion occur with a qene frequency of 0.18 while four variants of a ζ qlobin qene deletion occur in 3% of the population with or without α-thalassemia. Another type of ζ qene deletion occurs in the context of a (ζα) -thalassemia in which all α and ζ qlobin qenes are deleted. Further variability of ζ globin genes is due to dimorphism of the ζ 1 or ψζ, 1 genes. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/82318 |
| Appears in Collections: | Scholarly Works - FacM&SSur |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Globin_gene_organisation_and_expression_1987.pdf | 2.06 MB | Adobe PDF | View/Open |
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