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https://www.um.edu.mt/library/oar/handle/123456789/136218| Title: | Genetic characterization of pituitary neuroendocrine tumours in the Maltese population |
| Authors: | Spiteri, Emma Jayne Tabone, Alison Gruppetta, Mark Pace, Nikolai Paul Vassallo, Josanne |
| Keywords: | Pituitary gland -- Tumors -- Genetic aspects Neuroendocrine tumors -- Genetic aspects Pituitary gland -- Tumors -- Malta -- Statistics Pituitary gland -- Tumors -- Patients -- Malta |
| Issue Date: | 2025-05 |
| Publisher: | Bioscientifica |
| Citation: | Spiteri, E. J., Tabone, A., Gruppetta, M., Pace, N. P., & Vassallo, J. (2025, May). Genetic characterization of pituitary neuroendocrine tumours in the Maltese population. Presented at the Joint Congress of ESPE and ESE 2025. Endocrine Abstracts, 110, P854. |
| Abstract: | Pituitary neuroendocrine tumours (PitNETs) have a prevalence of 75.7/100,000 within the Maltese population. These tumours present a wide range of clinical behaviours, from hormone overproduction to local effects secondary to compression of adjacent structures, making them a significant public health concern. Despite their prevalence, the genetic factors contributing to sporadic PitNETs, which account for 95% of all cases, remain poorly understood. The primary aim of this study was to identify genetic variants associated with PitNETs in Maltese patients using germline whole exome sequencing, thereby contributing to the global understanding of the genetic aetiology of these tumours. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/136218 |
| Appears in Collections: | Scholarly Works - FacM&SMed |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Genetic characterization of pituitary neuroendocrine tumours in the Maltese population 2025.pdf | 90.37 kB | Adobe PDF | View/Open |
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