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https://www.um.edu.mt/library/oar/handle/123456789/136668| Title: | Replication of established type 2 diabetes susceptibility loci in the Maltese and Libyan populations |
| Authors: | Saadeddin Eljali, S. Pace, Nikolai Paul Felice, Alex E. Vassallo, Josanne |
| Keywords: | Type 2 diabetes -- Genetic aspects Type 2 diabetes -- Malta -- Case studies Type 2 diabetes -- Libya -- Case studies Diabetes -- Malta -- Epidemiology Diabetes -- Libya -- Epidemiology |
| Issue Date: | 2018 |
| Publisher: | University of Malta. Medical School |
| Citation: | Saadeddin Eljali, S., Pace, N., Felice, A., & Vassallo, J. (2018). Replication of established type 2 diabetes susceptibility loci in the Maltese and Libyan populations. Malta Medical Journal, 30(S), 191-192. |
| Abstract: | Introduction: Type 2 diabetes is a common complex
disorder with a high prevalence of the Maltese population.
The specific aim for this study was to further explore the
genetic interplay between selected genes from metabolic
and inflammatory pathways on the likelihood of developing
T2DM among selected clinical cohorts with the disease. Methods: 4 T2DM cohorts from previous investigations (Pace, 2013 & Al Ashtar, 2008) were recruited, theses are: group1- 96 heterogenous collection of Maltese T2DM. group 2- 199 heterogenous collection of Libyan T2DM patients. group3- 177 treatment-naïve group used to explore genotype-phenotype association group4- 198 high-morbidity group with end-organ complications. A collection of randomanomymised Maltese (n=200) and Libyan (n=198) neonatal cord blood samples Malta Bio Bank was used as reference control population. Genotyping of 18 known susceptibility loci was carried out in all cohorts. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/136668 |
| ISSN: | 18133339 |
| Appears in Collections: | Scholarly Works - FacM&SMed |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Replication of established type 2 diabetes susceptibility loci in the Maltese and Libyan populations 2018.pdf | 144.18 kB | Adobe PDF | View/Open |
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