Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/143975| Title: | Transposable elements in human cancer |
| Authors: | Grech, Alfred West, Stephen |
| Keywords: | Transposons Cancer -- Genetic aspects Molecular genetics Human genome |
| Issue Date: | 2022 |
| Publisher: | Medical Portals Ltd |
| Citation: | Grech, A., & West, S. (2022). Transposable elements in human cancer. The Synapse : the Medical Professionals' Network, 21(2), 15-18. |
| Abstract: | Transposable elements are repetitive DNA sequences consisting of RNA transposons, DNA transposons, and endogenous retroviruses. Repetitive sequences cover more than two-thirds of the genome in humans and transposable elements comprise the majority of the repetitive sequences (approximately 50% of the human genome). Transposable elements can transpose (i.e. can jump) and cause havoc. Indeed, research is showing that their deregulation impinges on the stability of the genome and on the regulation of transcription and that of non-coding RNA. This leads to carcinogenesis and to cancer progression. These insights are furthering their research to discover novel targets for theranostic applications in cancer. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/143975 |
| Appears in Collections: | The Synapse, Volume 21, Issue 2 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| TheSynapse21(2)A3.pdf | 3.14 MB | Adobe PDF | View/Open |
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