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https://www.um.edu.mt/library/oar/handle/123456789/145623| Title: | Interactions of coagulation Factor II G20210A and Factor V Leiden with cardiovascular risk factors increase risk of myocardial infarction |
| Authors: | Camilleri, J. A. Borg Carbott, F. Attard, Ritienne Dingli, Philip Doggen, Carine J. M. Cassar, Karen Farrugia, Rosienne Bezzina Wettinger, Stephanie |
| Keywords: | Blood coagulation factors Blood coagulation disorders Cardiovascular system Blood -- Circulation Myocardial infarction |
| Issue Date: | 2016 |
| Publisher: | Nature Publishing Group |
| Citation: | Camilleri, J. A., Borg Carbott, F., Attard, R., Dingli, P., Doggen, C. J. M., Cassar, K.,... Bezzina Wettinger, S. (2016, May). Interactions of coagulation Factor II G20210A and Factor V Leiden with cardiovascular risk factors increase risk of myocardial infarction. European Society of Human Genetics ESHG 2016, Spain. 129. |
| Abstract: | Introduction: The effect of Coagulation Factor II G20210A (FIIG20210A) and Factor V Leiden (FVL) combined with cardiovascular risk factors on the risk of myocardial infarction (MI) was studied in a Maltese population. Methods: Samples from the Maltese Acute Myocardial Infarction (MAMI) study including 423 cases with first MI and 465 controls were tested for the FVL and FIIG20210A mutations using PCR-RFLP with MnlI and HindIII re spectively. Interactions with lifestyle and metabolic risk factors were tested using data from questionnaires and medical history. Odds ratios (OR) and 95% confidence intervals (95%CI) were calculated to estimate the risk of MI overall and in subgroups. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/145623 |
| Appears in Collections: | Scholarly Works - FacHScABS |
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|---|---|---|---|---|
| Interactions_of_coagulation_Factor_II_G20210A_and_Factor_V_Leiden_with_cardiovascular_risk_factors_increase_risk_of_myocardial_infarction_2016.pdf | 273.73 kB | Adobe PDF | View/Open |
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