Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/147681
Title: Potential impact of increasing physical activity on NCD mortality in the EU : pathways to SDG 3.4.1 by 2030
Authors: Muhlis, Abdu Nafan Aisul
Mahrouseh, Nour
Soares Andrade, Carlos Alexandre
Chen-Xu, José
Eikemo, Terje Andreas
Balaj, Mirza
Economou, Mary
Mechili, Enkeleint A.
Unim, Brigid
Baravelli, Carl Michael
Badache, Andreea
Spijker, Jeroen
Gabrani, Jonila
Vieira, Rafael José
Lassen, Brian
Haneef, Romana
Tecirli, Gülcan
Cuschieri, Sarah
Rojas-Rueda, David
Hoven, Hanno
Chamouni, Ghenwa
Tarek, Gabriella Laila
Varga, Orsolya
Keywords: Exercise -- European Union countries -- Health aspects
Chronic diseases -- Mortality -- European Union countries
Sustainable Development Goals
Medicine, Preventive -- European Union countries
Public health -- Mathematical models
Issue Date: 2026
Publisher: BMJ Publishing Group LTD
Citation: Muhlis, A.N., Mahrouseh, N, Soares Andrade, C.A., Chen-Xu, J., Eikemo, T.A., Balaj, M.,…Varga, O. (2026). Potential impact of increasing physical activity on NCD mortality in the EU: pathways to SDG 3.4.1 by 2030. BMJ Global Health, 11: e022998.
Abstract: Background: Physical inactivity affects 36.2% of adults in the European Union (EU), contributing substantially to the burden of non-communicable diseases (NCDs). The WHO’s Global Action Plan on Physical Activity 2018–2030 targets a 15% relative reduction in physical inactivity by 2030, supporting Sustainable Development Goal (SDG) 3.4.1 to achieve over 30% reduction in premature NCD mortality. This study estimates the number of averted deaths, premature deaths and cause-specific NCD deaths averted if physical activity targets are achieved across EU countries.
Methods: We applied the WHO Preventable Risk Integrated ModEl using baseline physical activity and body mass index from waves 2 and 3 of the European Health Interview Survey. The counterfactual scenario modelled a 15% increase in metabolic equivalent of task hours/week of moderate-to-vigorous physical activity and a 15% relative reduction in the proportion of adults who are physically inactive across the EU.
Findings: Increased physical activity is associated with an estimated 24 178 premature deaths averted by 2030 (95% uncertainty interval (UI): 23 253–25 103), equivalent to 3.3% of premature NCD mortality. Overall, 107 108 deaths (95% UI: 102 479–111 737) across all ages could be prevented, representing 4.7% of total NCD deaths in EU member states.
Interpretation: Increasing physical activity alone is unlikely to achieve the SDG 3.4.1 target of reducing premature NCD deaths by 2030. However, when combined with other WHO ‘best buy’ interventions, such as improved diet and reduced tobacco and alcohol use, this target could be attainable across the EU.
URI: https://www.um.edu.mt/library/oar/handle/123456789/147681
Appears in Collections:Scholarly Works - FacM&SAna



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