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|Title:||Genetic determinants of visceral adiposity in Type 2 diabetes mellitus|
|Authors:||Pace, Nikolai Paul|
Felice, Alex E.
Obesity -- Malta -- Case studies
|Publisher:||University of Malta|
|Citation:||Pace, N. P., Vassallo, J., & Felice, A. E. (2015). Genetic determinants of visceral adiposity in Type 2 diabetes mellitus. In 9th Malta Medical School Conference, Malta.|
|Abstract:||Obesity is a heritable trait that arises from complex gene-environment interactions and is rapidly increasing in prevalence. It is defined by anthropometric measures such as the body mass index (BMI) and waist circumference (WC). A large number of single nucleotide variants (SNVs) have been repeatedly associated with visceral adiposity and related traits in various populations using a hypothesis-free GWAS approach. Despite the robust genomic association reported in the literature, GWAS-identified loci often show poor reproducibility and deficient phenotype associations when investigated in other populations.|
|Appears in Collections:||Scholarly Works - FacM&SPB|
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