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Title: Genetic determinants of visceral adiposity in Type 2 diabetes mellitus
Authors: Pace, Nikolai Paul
Vassallo, Josanne
Felice, Alex E.
Keywords: Obesity, abdominal
Obesity -- Malta -- Case studies
Diabetes Mellitus
Issue Date: 2015-12
Publisher: University of Malta
Citation: Pace, N. P., Vassallo, J., & Felice, A. E. (2015). Genetic determinants of visceral adiposity in Type 2 diabetes mellitus. In 9th Malta Medical School Conference, Malta.
Abstract: Obesity is a heritable trait that arises from complex gene-environment interactions and is rapidly increasing in prevalence. It is defined by anthropometric measures such as the body mass index (BMI) and waist circumference (WC). A large number of single nucleotide variants (SNVs) have been repeatedly associated with visceral adiposity and related traits in various populations using a hypothesis-free GWAS approach. Despite the robust genomic association reported in the literature, GWAS-identified loci often show poor reproducibility and deficient phenotype associations when investigated in other populations.
Appears in Collections:Scholarly Works - FacM&SPB

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