Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/48684
Title: A simple HPLC-UV method for the analysis of ciprofloxacin in tissue
Authors: Vella, Janis
Vella, Maria
Sammut Bartolo, Nicolette
Sammut, Carmel
Ferrito, Victor
Serracino-Inglott, Anthony
Azzopardi, Lilian M.
LaFerla, Godfrey
Keywords: Ciprofloxacin
Drugs -- Analysis
High performance liquid chromatography -- Methodology
Antibiotics
Issue Date: 2015-09
Publisher: University of Malta. Department of Pharmacy
Citation: Vella, J., Vella, M., Sammut Bartolo, N., Sammut, C., Ferrito, V., Serracino-Inglott, A.,...LaFerla, G. (2015, September). A simple HPLC-UV method for the analysis of ciprofloxacin in tissue. Poster session presented at the FIP 75th World Congress of Pharmacy and Pharmaceutical Sciences, Düsseldorf, Germany.
Abstract: A poster presentation regarding a simple HPLC-UV method for the analysis of ciprofloxacin in tissue. Introduction: The analysis of drugs in tissue is employed in various fields. Quantitative analysis of drugs in tissue may be applied to better relate concentrations with pharmacokinetic and pharmacodynamic responses and to understand therapeutic and toxic properties. There are no current validation guidelines which instruct and help the analyst with the homogenisation, extraction and analysis of drugs or molecules in solid samples. Calculating actual recovery and stability of the analyte of interest in tissue can be described as being difficult. Aims: To validate a simple, robust, rapid and efficient High Performance Liquid Chromatographic method of analysis to quantify ciprofloxacin– a popular and widely used antibiotic in tissue.
URI: https://www.um.edu.mt/library/oar/handle/123456789/48684
Appears in Collections:Scholarly Works - FacM&SPha

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