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https://www.um.edu.mt/library/oar/handle/123456789/53387| Title: | Glutamate and purine catabolites in relation to free radical production during focal ischemia-reperfusion : an in vivo study in cats |
| Authors: | Valentino, Mario Graf, Rudolf Toyota, Shingo Dohmen, Christian Gabel, P. Heiss, Wolf-Dieter |
| Keywords: | Glutamic acid Free radical reactions Cerebral ischemia |
| Issue Date: | 2001 |
| Publisher: | Lippincott Williams & Wilkins, Inc. |
| Citation: | Valentino, M., Graf, R., Toyota, S., Dohmen, C., Gabel, P., & Heiss, W. D. (2001). Glutamate and purine catabolites in relation to free radical production during focal ischemia-reperfusion: an in vivo study in cats. Journal of Cerebral Blood Flow and Metabolism, 21, S287-S287. |
| Abstract: | The in-vivo interrelation between excitotoxicity and oxidative stress following cerebral ischemia in cats was investigated. To elucidate the role of this mechanism in cerebral ischemia, the study presented herein sought to investigate the spatial and temporal features of the free radical response to elevations of glutamate and purine catabolites in a reproducible model of in vivo focal ischemia/reperfusion. The time course of neurochemical and Reactive Oxygen Species (ROS) were simultaneously conducted in ischemic focus and perifocal region of the brain. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/53387 |
| Appears in Collections: | Scholarly Works - FacM&SPB |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 25. Glutamate and purine catabolites in releation to free radical production during focal ischemia and reperfusion. An in vivo study in cats..pdf | 50.32 kB | Adobe PDF | View/Open |
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