Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/70946
Title: Colistin in burn intensive care : back to the future?
Authors: Azzopardi, Ernest A.
Boyce, Dean E.
Thomas, David W.
Dickson, William A.
Keywords: Colistin -- Therapeutic use
Gram-negative bacterial infections -- Chemotherapy
Multidrug resistance -- Databases
Antibacterial agents -- Evaluation
Surgery, Operative
Burns and scalds -- Treatment
Issue Date: 2013
Publisher: Elsevier
Citation: Azzopardi, E. A., Boyce, D. E., Thomas, D. W., & Dickson, W. A. (2013). Colistin in burn intensive care: back to the future?. Burns, 39(1), 7-15.
Abstract: Colistin is a venerable antibiotic whose fortunes have been revived by its excellent activity, the diminishing output of novel clinically effective antibiotics and the increasing importance of MDR infection in burn surgery, both in the civilian and military arenas. This review synthesizes current evidence on the usage of colistin in burn surgery including the structure– activity relationship; dosing, pharmacokinetics/pharmacodynamic (PK/PD), analytic methods, resistance and current research efforts into the redevelopment of this antibiotic, to distil recommendations for future research and clinical efficacy.
URI: https://www.um.edu.mt/library/oar/handle/123456789/70946
Appears in Collections:Scholarly Works - FacM&SAna

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