Guest lecture : hunterian lecture : multidrug resistant burn wound infection : establishing the causative profile and novel translatable theranostic strategies

Abstract

Multidrug resistant surgical infection is a global threat to the practice of surgery. This work is the first to describe a characteristic spectrum of Gram-negative bacteria to infect burn wounds, establish a clinically viable mechanism for passive drug accumulation and “smart release” at any infected soft tissue site. This work subsequently established an entirely novel class of macromolecular antibiotics.